Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.32 |
| ▸ | PPARD | Q03181 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607761 | 0.89 | VDR (0.45) | VDRS1PR1S1PR5PDGFRAROCK1 | |
| SCHEMBL7610926 | 0.89 | VDR (0.42) | VDRS1PR1S1PR5PDGFRAROCK1 | |
| SCHEMBL7608523 | 0.85 | VDR (0.41) | VDRFFAR1FFAR4 | |
| SCHEMBL7606174 | 0.84 | VDR (0.53) | VDRS1PR1S1PR5PDGFRAROCK1 | |
| SCHEMBL7647330 | 0.83 | FFAR1 (0.44) | VDRFFAR1 | |
| SCHEMBL7610503 | 0.82 | VDR (0.42) | VDRFFAR1FFAR4 | |
| SCHEMBL7613344 | 0.82 | RXRA (0.34) | VDRFFAR1 | |
| SCHEMBL7611578 | 0.82 | VDR (0.43) | VDRS1PR1S1PR5PDGFRAROCK1 | |
| SCHEMBL7607682 | 0.81 | VDR (0.44) | VDRFFAR1 | |
| SCHEMBL7610502 | 0.79 | VDR (0.42) | VDRFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |