Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319882 | 0.85 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL959919 | 0.81 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL27470232 | 0.80 | HDAC6 (0.33) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL9983224 | 0.79 | CA14 (0.32) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL27417576 | 0.77 | HDAC6 (0.33) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL19641951 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL1309204 | 0.76 | CA14 (0.41) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL21664460 | 0.74 | CA14 (0.35) | CA14 | |
| SCHEMBL2909639 | 0.74 | CA14 (0.38) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL1401436 | 0.74 | AKT1 (0.39) | AKT1HDAC6HDAC1HDAC2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192465-A1 | DETECTION USING DENDRIMERS BEARING LABELS AND PROBES | DAKO A/S (DK) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001002861-A1 | DETECTION USING DENDRIMERS BEARING LABELS AND PROBES | DAKO A/S (DK) | 2001-01-11 | — | — | WO | disclosed |