SCHEMBL959919

SCHEMBL959919

CC(C)(C)OC(=O)N(CCN)C(=O)CON

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512143 0.85 HDAC6 (0.33) HDAC6HDAC1HDAC2CA14
SCHEMBL28319882 0.84 HDAC6 (0.37) HDAC6HDAC1HDAC2CA14
SCHEMBL7612342 0.81 AKT1 (0.35) HDAC6HDAC1HDAC2CA14
SCHEMBL27470232 0.79 HDAC6 (0.33) HDAC6HDAC1HDAC2CA14
SCHEMBL27417576 0.76 HDAC6 (0.33) HDAC6HDAC1HDAC2CA14
SCHEMBL963261 0.75 HDAC6 (0.38) HDAC6HDAC1HDAC2CA14
SCHEMBL9983224 0.75 CA14 (0.32) HDAC6HDAC1HDAC2CA14
SCHEMBL1309204 0.75 CA14 (0.41) HDAC6HDAC1HDAC2CA14
SCHEMBL8697011 0.73 CA14 (0.37) HDAC6HDAC1HDAC2CA14
SCHEMBL2909639 0.73 CA14 (0.38) HDAC6HDAC1HDAC2CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456749-B1 A SUBSTITUTED POLYVINYL ALCOHOL REAGENT PVAC MEDICAL TECH LTD (CY) 2021-07-14 EP disclosed
EP-3456749-A1 A SUBSTITUTED POLYVINYAL ALCOHOL REAGENT PVAC Medical Technologies Ltd. (CY) 2019-03-20 EP disclosed
EP-2254944-B1 COMPOSITION FOR THE FORMATION OF GELS PVAC MEDICAL TECH LTD (CY) 2018-12-19 EP disclosed
US-9585987-B2 Composition for the formation of gels PVAC MEDICAL TECHNOLOGIES LTD (CY) 2017-03-07 US disclosed
US-20110008444-A1 COMPOSITION FOR THE FORMATION OF GELS IPR-SYSTEMS SWEDEN AB (SE) 2011-01-13 US disclosed
EP-2254944-A1 COMPOSITION FOR THE FORMATION OF GELS IPR-Systems Sweden AB (SE) 2010-12-01 EP disclosed
WO-2009108100-A1 COMPOSITION FOR THE FORMATION OF GELS IPR-SYSTEMS SWEDEN AB (SE) 2009-09-03 WO disclosed