Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884537 | 0.83 | HDAC6 (0.44) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL8806268 | 0.83 | HDAC6 (0.41) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL1706932 | 0.80 | HDAC6 (0.38) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL5580137 | 0.80 | AKT1 (0.39) | AKT1HDAC6HDAC1HDAC2NFKB1 | |
| SCHEMBL17232564 | 0.79 | HDAC6 (0.41) | AKT1HDAC6HDAC1HDAC2NFKB1 | |
| SCHEMBL5555258 | 0.78 | HDAC6 (0.57) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL963261 | 0.78 | HDAC6 (0.38) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL3884535 | 0.77 | HDAC6 (0.40) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL15734005 | 0.76 | NFKB1 (0.44) | HDAC6HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL4676227 | 0.76 | HDAC6 (0.46) | HDAC6HDAC1HDAC2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800545-B2 | TARGETED MAGNETICALLY LABELED MOLECULAR MARKER SYSTEMS FOR THE NMR IMAGING | BRACCO RESEARCH SA (CH) | 2011-03-02 | — | — | EP | disclosed |
| EP-0800545-B1 | TARGETED MAGNETICALLY LABELED MOLECULAR MARKER SYSTEMS FOR THE NMR IMAGING | BRACCO RESEARCH SA (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-5910300-A | AN MRI CONTRAST AGENT COMPRISING A MAGNETICALLY-RESPONSIVE, HYDROPHOBIC PARTICLE HYDROGEN BONDED TO AN AMPHIPHILIC POLYMER/ADDUCT MODIFIED BY A COMPOUND HAVING BIOAFFINITY FOR THE PHYSIOLOGICAL TARGET; MOBILITIY; OPSONIZATION RESISTANCE | BRACCO RESEARCH S.A. (CH) | 1999-06-08 | — | — | US | disclosed |
| EP-0800545-A1 | TARGETED MAGNETICALLY LABELED MOLECULAR MARKER SYSTEMS FOR THE NMR IMAGING | BRACCO RESEARCH S.A. (CH) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997016474-A1 | TARGETED MAGNETICALLY LABELED MOLECULAR MARKER SYSTEMS FOR THE NMR IMAGING | BRACCO RESEARCH S.A. (CH) | 1997-05-09 | — | — | WO | disclosed |