Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607256 | 0.88 | NPSR1 (0.69) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7606200 | 0.83 | NPSR1 (0.63) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL8721193 | 0.83 | NPSR1 (0.60) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7614793 | 0.82 | KDM4E (0.65) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7606969 | 0.82 | KDM4E (0.67) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL8338308 | 0.80 | KDM4E (0.77) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7645488 | 0.80 | KDM4E (0.74) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL16649171 | 0.80 | NPSR1 (0.73) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL9360287 | 0.80 | NPSR1 (0.70) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7617870 | 0.80 | KDM4E (0.69) | NPSR1CYP1A2CYP2C19KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207154-A1 | Herbicidal carboxamide derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-0447004-B1 | Herbicidal carboxamide derivatives | SHELL INT RESEARCH (NL) | 1998-01-28 | — | — | EP | disclosed |
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | disclosed |
| US-5294597-A | 2-((Halophenyl)amido-)m,6-((halophenyl)oxy-)pyridines | SHELL RESEARCH LIMITED (GB) | 1994-03-15 | — | — | US | disclosed |
| EP-0447004-A2 | Herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-18 | — | — | EP | disclosed |