Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.64 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | RET | P07949 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612484 | 0.88 | NPSR1 (0.66) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7617870 | 0.84 | KDM4E (0.69) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7606200 | 0.83 | NPSR1 (0.63) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL7645488 | 0.82 | KDM4E (0.74) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL8338308 | 0.82 | KDM4E (0.77) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| Diflufenican SCHEMBL22023 | 0.82 | KMT2A (1.00) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| Diflufenican SCHEMBL29373740 | 0.82 | KMT2A (1.00) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| Diflufenican SCHEMBL8536896 | 0.82 | KMT2A (1.00) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| Diflufenican SCHEMBL29549369 | 0.82 | KMT2A (1.00) | NPSR1CYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL19878491 | 0.81 | KDR (0.78) | NPSR1CYP1A2CYP2C19KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207154-A1 | Herbicidal carboxamide derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-0447004-B1 | Herbicidal carboxamide derivatives | SHELL INT RESEARCH (NL) | 1998-01-28 | — | — | EP | disclosed |
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | disclosed |
| EP-0447004-A2 | Herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-18 | — | — | EP | disclosed |