Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | P2RY1 | P47900 | 17/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645488 | 0.88 | KDM4E (0.74) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL8536896 | 0.87 | KMT2A (1.00) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL29549369 | 0.87 | KMT2A (1.00) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL29373740 | 0.87 | KMT2A (1.00) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL22023 | 0.87 | KMT2A (1.00) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3150129 | 0.84 | P2RY1 (1.00) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL28864547 | 0.84 | KMT2A (0.93) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7607256 | 0.82 | NPSR1 (0.69) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| Diflufenican SCHEMBL21295280 | 0.81 | KMT2A (0.88) | KDM4EMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL16649171 | 0.81 | NPSR1 (0.73) | KDM4EMEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939359-A | Herbicidal pyrazine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| EP-0773934-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003391-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |