Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23373570 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPK1KDM4EGAAMAPT | |
| SCHEMBL5716258 | 0.75 | TSHR (0.38) | ALDH1A1KDM4EMAPTHTTCNR2 | |
| SCHEMBL24248012 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPK1KDM4EGAAMAPT | |
| SCHEMBL5716284 | 0.74 | TSHR (0.48) | ALDH1A1MAPK1MAPTCNR2CNR1 | |
| SCHEMBL6791387 | 0.74 | PSEN1 (0.37) | ALDH1A1HPGD | |
| SCHEMBL13181094 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPK1KDM4EGAAMAPT | |
| SCHEMBL7612924 | 0.71 | TAAR1 (0.35) | ALDH1A1MAPK1HPGDTAAR1TDP1 | |
| SCHEMBL13675162 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPK1KDM4EGAAMAPT | |
| SCHEMBL22257241 | 0.71 | TRPA1 (0.50) | ALDH1A1HPGDLMNAMAOAMAOB | |
| SCHEMBL19231862 | 0.71 | TRPA1 (0.50) | ALDH1A1HPGDLMNAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252166-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001042249-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2001-06-14 | — | — | WO | disclosed |