Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.88 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.88 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913833 | 1.00 | CHRM1 (0.88) | CHRM1CHRM4SIGMAR1 | |
| Oxalic Acid SCHEMBL7619712 | 0.95 | CHRM1 (0.79) | CHRM1CHRM4 | |
| Oxalic Acid SCHEMBL7616498 | 0.95 | CHRM1 (0.79) | CHRM1CHRM4 | |
| SCHEMBL8189299 | 0.94 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL8189336 | 0.94 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL8196563 | 0.93 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL8196549 | 0.90 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL6915120 | 0.89 | CHRM1 (0.91) | CHRM1CHRM4 | |
| SCHEMBL6911698 | 0.89 | CHRM1 (0.91) | CHRM1CHRM4 | |
| Tazomeline SCHEMBL195235 | 0.89 | CHRM1 (0.91) | CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734259-B1 | Use of piperidine compounds in the treatment of schizophrenia | NOVO NORDISK AS (DK) | 2002-06-12 | — | — | EP | claimed |
| US-5753683-A | SCHIZOPHRENIA | NOVO NORDISK A/S (DK) | 1998-05-19 | — | — | US | claimed |
| US-5744489-A | ADMINISTERING CERTAIN 1,2,5-THIADIAZOLE AND 1,2,5-OXADIAZOLE COMPOUNDS | GREENWOOD BEVERLEY (US) | 1998-04-28 | — | — | US | claimed |
| EP-0788357-A1 | A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS | NOVO NORDISK A/S (DK) | 1997-08-13 | — | — | EP | claimed |
| EP-0734259-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1996-10-02 | — | — | EP | claimed |
| WO-1996014066-A1 | A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS | NOVO NORDISK A/S (DK) | 1996-05-17 | — | — | WO | claimed |
| EP-0687265-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-12-20 | — | — | EP | claimed |
| WO-1995005174-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1995-02-23 | — | — | WO | claimed |
| WO-1994020495-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-09-15 | — | — | WO | claimed |
| EP-0709094-B1 | Tetrahydropyridine oxadiazole or thiadiazole compound for treating anxiety | LILLY CO ELI (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5708014-A | SUBSTITUTED TETRAHYDROPYRIDINYL-1,2,5-OXADIAZOLES OR THIADIAZOLES | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0709094-A2 | Method for treating anxiety using a tetrahydropyridine oxadiazole or thiadiazole compound | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |