Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 7/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018319 | 1.00 | — | — | |
| SCHEMBL7611194 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL5481202 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL5586092 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL2025361 | 0.97 | — | — | |
| SCHEMBL6706888 | 0.87 | FAAH (0.52) | GMNNTP53POLBMAPTCYP2C9 | |
| SCHEMBL2018589 | 0.77 | — | — | |
| SCHEMBL3265077 | 0.75 | TSHR (0.41) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL3507116 | 0.74 | — | — | |
| SCHEMBL9451397 | 0.74 | TSHR (0.42) | TSHRTHRBCES2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342611-B1 | BLOCKED RHODAMINE DERIVATIVES | CYTOVIA, INC. | 2002-01-29 | — | — | US | claimed |