⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761337 | 0.82 | — | — | |
| SCHEMBL3817007 | 0.63 | — | — | |
| SCHEMBL3819741 | 0.62 | — | — | |
| SCHEMBL34680 | 0.62 | — | — | |
| SCHEMBL9935782 | 0.62 | — | — | |
| SCHEMBL622255 | 0.62 | — | — | |
| SCHEMBL1628000 | 0.62 | — | — | |
| SCHEMBL17102937 | 0.62 | — | — | |
| SCHEMBL8975369 | 0.62 | — | — | |
| SCHEMBL27472571 | 0.62 | INMT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1320880-C | Improved formulation for topical non-invasive application in vivo | IDEA INNOVAT DERMALE APPL GMBH (DE) | 2007-06-13 | — | — | CN | claimed |
| EP-0837052-B1 | BICYCLIC AMINO DERIVATIVES AND PGD 2 ANTAGONIST CONTAINING THE SAME | SHIONOGI & CO (JP) | 2006-08-23 | — | — | EP | claimed |
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | claimed |
| US-6498190-B1 | TREATMENT OF NASAL OCCLUSION AND MAST CELL DYSFUNCTION DISEASES; ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2002-12-24 | — | — | US | claimed |
| US-6384075-B1 | TREATING DISEASES IN WHICH MAST CELL DYSFUNCTION IS INVOLVED | SHIONOGI & CO., LTD. (JP) | 2002-05-07 | — | — | US | claimed |
| US-6172113-B1 | Bicyclic amino derivatives and PGD2 antagonist containing the same | SHIONOGI & CO., LTD. (JP) | 2001-01-09 | — | — | US | claimed |
| CN-1193315-A | Bicyclic amino derivatives and PGDZ antagonist containing same | SHIONOGI PHARMACEUTIC K K (JP) | 1998-09-16 | — | — | CN | claimed |
| EP-0837052-A1 | BICYCLIC AMINO DERIVATIVES AND PGD 2 ANTAGONIST CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1998-04-22 | — | — | EP | claimed |
| US-12410116-B2 | Compounds and use thereof in methods of treatment | THE UNIVERSITY OF QUEENSLAND (AU) | 2025-09-09 | — | — | US | disclosed |
| US-20240002326-A1 | COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-04 | — | — | US | disclosed |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-03-30 | — | — | US | disclosed |
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-3210627-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2022-12-21 | — | — | EP | disclosed |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-09-06 | — | — | US | disclosed |
| CN-1193315-A | Bicyclic amino derivatives and PGDZ antagonist containing same | SHIONOGI PHARMACEUTIC K K (JP) | 1998-09-16 | — | — | CN | disclosed |
| EP-0837052-A1 | BICYCLIC AMINO DERIVATIVES AND PGD 2 ANTAGONIST CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1998-04-22 | — | — | EP | disclosed |
| CN-1097007-A | Process for preparing 2-iminothiazoline derivatives and process for preparing intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1995-01-04 | — | — | CN | disclosed |
| US-4365989-A | 2-Thiocyanomethylthio-4,4-dialkyl-5-substituted-thiazoline fungicides | CHEVRON RESEARCH COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-3943142-A | Dye intermediates and their preparation and use in the synthesis of methine dyes | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3943142-A | Dye intermediates and their preparation and use in the synthesis of methine dyes | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | disclosed |