Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NCK1 | P16333 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824503 | 1.00 | CYP2A6 (0.56) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL24621868 | 0.91 | CYP2A6 (0.54) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL13670757 | 0.91 | CYP2A6 (0.54) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL2616771 | 0.91 | CYP2A6 (0.59) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL30969150 | 0.91 | CYP2A6 (0.59) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL8338092 | 0.84 | PRKCZ (0.68) | CYP1A2PRKCZIMPDH2MELKF9 | |
| SCHEMBL23555378 | 0.84 | PRKCZ (0.68) | CYP1A2PRKCZIMPDH2MELKF9 | |
| SCHEMBL13615233 | 0.84 | PRKCZ (0.53) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 | |
| SCHEMBL17666296 | 0.82 | PRKCZ (0.51) | CYP1A2PRKCZF9PRKCITDO2 | |
| SCHEMBL19321774 | 0.81 | CYP1A2 (0.46) | CYP2A6CYP1A2PRKCZTDP1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1082 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014858-A | Process for preparing polysubstituted indolizine derivatives | 淮阴师范学院 | 2022-02-08 | — | — | CN | claimed |
| CN-107973388-A | A kind of particulate matter filler for being used to strengthen ultrasonic oxygen-enriching device | 北京中科宇清环保有限公司 | 2018-05-01 | — | — | CN | claimed |
| CN-107792937-A | A kind of ultrasound-enhanced oxygen-enriching device based on micro-nano attenuating fluid | 北京中科宇清环保有限公司 | 2018-03-13 | — | — | CN | claimed |
| EP-2091929-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | The European Molecular Biology Laboratory (DE) | 2009-08-26 | — | — | EP | claimed |
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | claimed |
| WO-2007107352-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-1703912-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | Jerini AG (DE) | 2006-09-27 | — | — | EP | claimed |
| WO-2005063259-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-07-14 | — | — | WO | claimed |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | disclosed |
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4463444-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2024-11-20 | — | — | EP | disclosed |
| EP-3651762-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2024108155-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024103126-A1 | TSPO LIGANDS | THE UNIVERSITY OF SYDNEY (AU) | 2024-05-23 | — | — | WO | disclosed |
| EP-0920414-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997049674-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-12-31 | — | — | WO | disclosed |
| EP-0014929-B1 | DIAGNOSTIC MEANS, PROCESS FOR ITS PREPARATION AND ITS USE IN DETERMINING LEUCOCYTES IN BODY FLUIDS | Roche Diagnostics GmbH (DE) | 1982-01-06 | — | — | EP | disclosed |
| US-4299917-A | IMPREGNATION OF AN ABSORBENT CARRIER WITH A SULPHONPHTHALEIN ESTER AND AN ACTIVATOR | BOEHRINGER MANNEHEIM GMBH (DE) | 1981-11-10 | — | — | US | disclosed |
| EP-0014929-A1 | Diagnostic means, process for its preparation and its use in determining leucocytes in body fluids | Roche Diagnostics GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-4053318-A | SENSITIZING MEROCYANINE DYE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | CYP2A6 2487/4885CYP1A2 1399/4885PRKCZ 965/4885 |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | VHL, CDKN1A, CCNI | CYP2A6 3732/4885CYP1A2 2245/4885PRKCZ 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.