Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.73 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.73 |
| ▸ | NQO2 | P16083 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941181 | 1.00 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1846496 | 0.86 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1567114 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7016328 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL2608948 | 0.84 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8065745 | 0.84 | MTNR1A (0.68) | MTNR1ANQO2 | |
| SCHEMBL5511489 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4043404 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1688124 | 0.83 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL30449793 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104178546-B | The method of optical voidness S-1-naphthalene ethylamine is prepared in a kind of fractionation | CHEN YONGJUN (CN) | 2017-01-04 | — | — | CN | claimed |
| CN-104164470-B | The method of optical voidness R-1-naphthalene ethylamine is prepared in a kind of fractionation | 六安佳诺生化科技有限公司 | 2016-12-21 | — | — | CN | claimed |
| CN-104178547-B | The method of optical voidness S-1-naphthalene ethylamine is prepared in a kind of fractionation | 陈永军 | 2016-12-07 | — | — | CN | claimed |
| CN-104151171-B | The method of optical voidness R-1-naphthalene ethylamine is prepared in a kind of fractionation | 六安佳诺生化科技有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-104178546-A | Method for preparing optically-pure S-1-naphthylethylamine through resolution | CHEN YONGJUN | 2014-12-03 | — | — | CN | claimed |
| CN-104178547-A | Method for preparing optically-pure S-1-naphthylethylamine through resolution | CHEN YONGJUN | 2014-12-03 | — | — | CN | claimed |
| CN-104164470-A | Method for preparing optically pure R-1-naphthylethylamine by resolution | CHEN YONGJUN | 2014-11-26 | — | — | CN | claimed |
| CN-104151171-A | Method for preparing optically pure R-1-naphthylethylamine by splitting | CHEN YONGJUN | 2014-11-19 | — | — | CN | claimed |
| EP-3551639-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018106621-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
| CN-104178546-B | The method of optical voidness S-1-naphthalene ethylamine is prepared in a kind of fractionation | CHEN YONGJUN (CN) | 2017-01-04 | — | — | CN | disclosed |
| CN-104178546-B | The method of optical voidness S-1-naphthalene ethylamine is prepared in a kind of fractionation | CHEN YONGJUN (CN) | 2017-01-04 | — | — | CN | disclosed |
| CN-104164470-B | The method of optical voidness R-1-naphthalene ethylamine is prepared in a kind of fractionation | 六安佳诺生化科技有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-104178547-B | The method of optical voidness S-1-naphthalene ethylamine is prepared in a kind of fractionation | 陈永军 | 2016-12-07 | — | — | CN | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
| WO-1999058496-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |
| US-5616614-A | USEFUL IN TREATMENT OF DISORDERS LINKED TO ABNORMAL MELATONIN ACTIVITY | ADIR ET COMPAGNIE (FR) | 1997-04-01 | — | — | US | disclosed |
| EP-0562956-B1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0562956-A1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-09-29 | — | — | EP | disclosed |