Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716333 | 0.99 | CYP4F2 (0.51) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL7708009 | 0.96 | CYP4F2 (0.53) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL7622711 | 0.91 | LTB4R (0.49) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL7619337 | 0.88 | CYP2D6 (0.44) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL8505531 | 0.87 | FFAR1 (0.52) | LTB4RLTB4R2PPARGFFAR1MMP8 | |
| SCHEMBL7714028 | 0.84 | FFAR1 (0.55) | LTB4RLTB4R2MAOBFFAR1MMP8 | |
| SCHEMBL7622533 | 0.84 | MMP8 (0.57) | PPARGPPARAMMP8ALDH1A1L3MBTL1 | |
| SCHEMBL7708014 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL7708036 | 0.83 | CYP4F2 (0.49) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 | |
| SCHEMBL7713972 | 0.83 | CYP4F2 (0.51) | CYP4F2CYP4A11CYP2D6LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |