Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614506 | 1.00 | L3MBTL1 (0.47) | L3MBTL1CYP11B2DRD2HDAC1DRD3 | |
| SCHEMBL7614509 | 1.00 | L3MBTL1 (0.47) | L3MBTL1CYP11B2DRD2HDAC1DRD3 | |
| SCHEMBL6178898 | 0.85 | DRD2 (0.39) | L3MBTL1CYP11B2DRD2HDAC1DRD3 | |
| SCHEMBL7614141 | 0.80 | USP2 (0.44) | DRD2HTTFNTAFNTBROCK2 | |
| SCHEMBL7614145 | 0.80 | USP2 (0.44) | DRD2HTTFNTAFNTBROCK2 | |
| SCHEMBL7614138 | 0.80 | USP2 (0.44) | DRD2HTTFNTAFNTBROCK2 | |
| SCHEMBL1514921 | 0.80 | MEN1 (0.50) | HDAC1ROCK2 | |
| SCHEMBL308318 | 0.78 | HDAC1 (0.46) | L3MBTL1CYP11B2DRD2HDAC1DRD3 | |
| SCHEMBL10224501 | 0.77 | HDAC1 (0.45) | L3MBTL1CYP11B2DRD2HDAC1DRD3 | |
| SCHEMBL7887368 | 0.76 | L3MBTL1 (0.45) | L3MBTL1CYP11B2DRD2HDAC1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471058-A | Process for preparing cephapirin analogues | 中国医学科学院药物研究所 | 2020-07-31 | — | — | CN | disclosed |
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| CN-1046524-C | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1999-11-17 | — | — | CN | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| CN-1105365-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1995-07-19 | — | — | CN | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |