Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961321 | 0.83 | HSD17B3 (0.49) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| SCHEMBL3421961 | 0.81 | HSD17B3 (0.47) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| SCHEMBL8569782 | 0.81 | HSD17B3 (0.64) | HSD17B3HTTAVPR1ABRPF1ALDH1A1 | |
| SCHEMBL31345695 | 0.81 | HSD17B3 (0.47) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| Hydrochloric Acid SCHEMBL736324 | 0.80 | HSD17B3 (0.46) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| SCHEMBL3988629 | 0.79 | HSD17B3 (0.45) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| SCHEMBL3089343 | 0.75 | SMN1; SMN2 (0.46) | HSD17B3AVPR1AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29556642 | 0.74 | HSD17B3 (0.47) | HSD17B3HTTAVPR1ACASP3CASP2 | |
| SCHEMBL6583411 | 0.74 | MAPK1 (0.49) | HSD17B3AVPR1ABRPF1MAPK1 | |
| SCHEMBL8304937 | 0.70 | BRPF1 (0.41) | HSD17B3HTTAVPR1ACASP3CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030886-A2 | HETEROCYCLIC ANGIOGENESIS INHIBITORS | MATTHEWS BARRY R (AU) | 2002-04-18 | — | — | WO | disclosed |