SCHEMBL8304937

SCHEMBL8304937

ON1CNc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.41
HSD17B3 P37058 1/20 0.39
GAA P10253 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
BRD4 O60885 2/20 0.35
AVPR1A P37288 1/20 0.33
HTT P42858 1/20 0.32
IDO1 P14902 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CASP3 P42574 1/20 0.31
CASP2 P42575 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OGFRL1 Q5TC84 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728158 0.78 AVPR1A (0.43) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL19270331 0.73
SCHEMBL28876634 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL17114712 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL30738818 0.73 BRPF1 (0.50) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL4265285 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL9521938 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL4013751 0.73 BRPF1 (0.50) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL21400260 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A
SCHEMBL10526824 0.73 BRPF1 (0.41) BRPF1HSD17B3GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0910565-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS Bayer Corporation (US) 1999-04-28 EP claimed
WO-1998035957-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS BAYER CORPORATION (US) 1998-08-20 WO claimed
EP-3080121-A1 FUSED TRICYCLIC BENZIMIDAZOLES DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SPRL (BE) 2016-10-19 EP disclosed
EP-3063240-A1 DISPERSANT'S WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS Lubrizol Advanced Materials, Inc. (US) 2016-09-07 EP disclosed
US-9287052-B2 Additives for dye-sensitized solar cells MERCK PATENT GMBH (DE) 2016-03-15 US disclosed
WO-2015086525-A1 FUSED TRICYCLIC BENZIMIDAZOLES DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB BIOPHARMA SPRL (BE) 2015-06-18 WO disclosed
WO-2015065829-A1 DISPERSANTS WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed
WO-2015066156-A1 DISPERSANT'S WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed
US-20130292601-A1 Additives for Dye-Sensitized Solar Cells MERCK PATENT GMBH (DE) 2013-11-07 US disclosed
EP-0910565-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS Bayer Corporation (US) 1999-04-28 EP disclosed
WO-1998035957-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS BAYER CORPORATION (US) 1998-08-20 WO disclosed