Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127458 | 0.91 | ALDH1A1 (0.50) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL4780119 | 0.86 | CASP3 (0.55) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL4782342 | 0.86 | CASP3 (0.55) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL4782347 | 0.86 | CASP3 (0.55) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL22559317 | 0.85 | ALDH1A1 (0.55) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL22559315 | 0.85 | ALDH1A1 (0.55) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL10324266 | 0.82 | ALDH1A1 (0.57) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL10324267 | 0.82 | ALDH1A1 (0.57) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL13919613 | 0.81 | POLB (0.51) | GLSALDH1A1CASP3MAPTNPSR1 | |
| SCHEMBL7286779 | 0.80 | CA12 (0.51) | GLSALDH1A1CASP3MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107196-A1 | Method for inducing chemotaxis in endothelial cells by administering stromal cell derived factor-1alpha | SMITHKLINE BEECHAM CORPORATION | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107196-A1 | Method for inducing chemotaxis in endothelial cells by administering stromal cell derived factor-1alpha | CXCL12, CXCR4, CCL2 | GLS 2389/4885ALDH1A1 2944/4885CASP3 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.