SCHEMBL7614929

SCHEMBL7614929

[CH]=CCC=CCCCCC=CCCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.56
PPARG P37231 3/20 0.50
FAAH O00519 3/20 0.50
FFAR1 O14842 2/20 0.50
PPARD Q03181 2/20 0.50
PPARA Q07869 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HSPD1 P10809 1/20 0.50
CYP19A1 P11511 1/20 0.50
FABP4 P15090 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143980 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL7614924 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL143981 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL7289665 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL21694666 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25181797 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL29284268 0.98 TRPV1 (0.59) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25178025 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25182431 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL21694668 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
EP-1229907-A1 PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS WARNER-LAMBERT COMPANY (US) 2002-08-14 EP disclosed
WO-2001034127-A1 PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-05-17 WO disclosed