SCHEMBL143980

SCHEMBL143980

[CH]=CC/C=C/CCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.56
PPARG P37231 3/20 0.50
FAAH O00519 3/20 0.50
FFAR1 O14842 2/20 0.50
PPARD Q03181 2/20 0.50
PPARA Q07869 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HSPD1 P10809 1/20 0.50
CYP19A1 P11511 1/20 0.50
FABP4 P15090 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7614924 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL143981 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL7614929 1.00 TRPV1 (0.56) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL7289665 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL21694666 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25181797 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL29284268 0.98 TRPV1 (0.59) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25178025 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL25182431 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD
SCHEMBL21694668 0.98 FAAH (0.54) TRPV1PPARGFAAHFFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230042328-A1 IONIC LIQUID FOR STABILIZING VISCOSITY OF SILICATE-BASED COATINGS BASF SE (DE) 2023-02-09 US disclosed
WO-2021122673-A1 IONIC LIQUID FOR STABILIZING VISCOSITY OF SILICATE-BASED COATINGS BASF SE (DE) 2021-06-24 WO disclosed
EP-3134380-B1 METHOD FOR PRODUCING CARBOXYLIC ACID ESTERS IN THE PRESENCE OF AN IONIC LIQUID AND AN ACIDIC ESTERIFICATION CATALYST AND THE USE THEREOF AS PLASTICIZER BASF SE (DE) 2019-08-14 EP disclosed
US-9776949-B2 Process for the production of carboxylic esters and use of these as plasticizers BASF SE (DE) 2017-10-03 US disclosed
US-20170174676-A1 CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2017-06-22 US disclosed
EP-3134380-A1 METHOD FOR PRODUCING CARBOXYLIC ACID ESTERS IN THE PRESENCE OF AN IONIC LIQUID AND AN ACIDIC ESTERIFICATION CATALYST AND THE USE THEREOF AS PLASTICIZER BASF SE (DE) 2017-03-01 EP disclosed
US-20170044085-A1 PROCESS FOR THE PRODUCTION OF CARBOXYLIC ESTERS AND USE OF THESE AS PLASTICIZERS BASF SE (DE) 2017-02-16 US disclosed
EP-2074255-B1 IONIC LIQUIDS FOR SOLUBILIZING POLYMERS BASF SE (DE) 2016-12-14 EP disclosed
US-9512354-B2 Chlorinated naphthalenetetracarboxylic acid derivatives, preparation thereof and use thereof in organic electronics BASF SE (DE) 2016-12-06 US disclosed
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP disclosed
EP-0719258-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP disclosed
WO-1996002508-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-02-01 WO disclosed
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
US-5306719-A Cardiotonic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
US-4845100-A WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 EP disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174676-A1 CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS SLCO2A1, SLCO2B1, SLC43A3 TRPV1 961/4885PPARG 278/4885FAAH 1134/4885
US-20170044085-A1 PROCESS FOR THE PRODUCTION OF CARBOXYLIC ESTERS AND USE OF THESE AS PLASTICIZERS FASN, ELOVL3, ELOVL5 TRPV1 2237/4885PPARG 128/4885FAAH 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.