Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615273 | 1.00 | CYP3A4 (0.35) | CYP3A4ALDH1A1ACEMAPTL3MBTL1 | |
| SCHEMBL7615268 | 1.00 | CYP3A4 (0.35) | CYP3A4ALDH1A1ACEMAPTL3MBTL1 | |
| SCHEMBL26361631 | 0.79 | FAAH (0.39) | CYP3A4ALDH1A1ACEMAPTL3MBTL1 | |
| SCHEMBL9000514 | 0.78 | CYP3A4 (0.37) | CYP3A4ALDH1A1MAPTL3MBTL1PIK3CD | |
| SCHEMBL4594212 | 0.77 | PIK3CD (0.55) | CYP3A4ALDH1A1MAPTL3MBTL1PIK3CD | |
| SCHEMBL1682219 | 0.77 | CYP3A4 (0.44) | CYP3A4ALDH1A1MAPTL3MBTL1PIK3CD | |
| SCHEMBL1551140 | 0.77 | CYP3A4 (0.35) | CYP3A4ALDH1A1ACEMAPTL3MBTL1 | |
| SCHEMBL7510369 | 0.76 | FPR2 (0.35) | ACEL3MBTL1PIK3CDNPSR1 | |
| SCHEMBL7619079 | 0.76 | FPR2 (0.35) | ACEL3MBTL1PIK3CDNPSR1 | |
| SCHEMBL7619075 | 0.76 | FPR2 (0.35) | ACEL3MBTL1PIK3CDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |