Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 10/20 | 0.38 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.38 |
| ▸ | INPP5B | P32019 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397735 | 0.85 | INPPL1 (0.35) | ESR1PDCD1ESR2CD274INPPL1 | |
| SCHEMBL7617241 | 0.85 | INPPL1 (0.37) | INPPL1INPP5AINPP5BTYRAKT1 | |
| SCHEMBL7622367 | 0.83 | INPPL1 (0.44) | ESR1PDCD1ESR2CD274INPPL1 | |
| SCHEMBL7619707 | 0.82 | POLB (0.37) | ESR1INPPL1INPP5AINPP5BTYR | |
| SCHEMBL6398355 | 0.82 | ESR1 (0.34) | ESR1ESR2INPPL1INPP5AINPP5B | |
| SCHEMBL6396820 | 0.80 | ESR1 (0.44) | ESR1ESR2INPPL1INPP5AINPP5B | |
| SCHEMBL7616672 | 0.80 | TDP1 (0.37) | ESR1ESR2INPPL1INPP5AINPP5B | |
| SCHEMBL7616785 | 0.79 | ESR1 (0.44) | ESR1PDCD1ESR2CD274INPPL1 | |
| SCHEMBL7616320 | 0.78 | ESR1 (0.46) | ESR1PDCD1ESR2CD274TYR | |
| SCHEMBL6397849 | 0.77 | ESR1 (0.43) | ESR1PDCD1ESR2CD274INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175425-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000043402-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-27 | — | — | WO | disclosed |