Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056155 | 0.92 | S1PR2 (0.46) | S1PR2S1PR4S1PR1S1PR3THRA | |
| SCHEMBL7615412 | 0.85 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3IGF1R | |
| SCHEMBL682183 | 0.85 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3IGF1R | |
| SCHEMBL7620776 | 0.85 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3IGF1R | |
| SCHEMBL7614058 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7620987 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7620869 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7614749 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7620024 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7615234 | 0.85 | MAPT (0.55) | LTB4RNPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |