Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620776 | 0.93 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3LTB4R | |
| SCHEMBL682183 | 0.93 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3LTB4R | |
| SCHEMBL7615412 | 0.93 | HDAC3 (0.49) | S1PR2S1PR4S1PR1S1PR3LTB4R | |
| SCHEMBL7614058 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7620987 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7614749 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7615234 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7620024 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7620869 | 0.93 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL7616078 | 0.92 | S1PR2 (0.44) | S1PR2S1PR4S1PR1S1PR3THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996011901-A1 | NOVEL α,α,α',α'-TETRACHLOROBICARBOXYLIC ACIDS, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |