SCHEMBL7616558

SCHEMBL7616558

C=CC(CNCCC[Si](OC)(OC)OC)NCc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ TSHR P16473 1/20 0.34
▸ CASR P41180 1/20 0.34
▸ SIGMAR1 Q99720 4/20 0.33
▸ SCN8A Q9UQD0 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26104985 0.82 SMN1; SMN2 (0.40) SMN1; SMN2TSHRCASRSIGMAR1GAA
SCHEMBL515863 0.79 SMN1; SMN2 (0.34) MAOASMN1; SMN2CHRM2TSHRSIGMAR1
SCHEMBL48855 0.78 MAOA (0.58) MAOACHRM2SIGMAR1SCN8AGAA
SCHEMBL25335334 0.77 MAOA (0.56) MAOACHRM2SIGMAR1SCN8AGAA
SCHEMBL20239078 0.77 MEN1 (0.42) MAOACHRM2GAAATM
Methylamine SCHEMBL3624091 0.76 MAOA (0.55) MAOACHRM2SIGMAR1SCN8AGAA
SCHEMBL144038 0.76 CHRM2 (0.58) MAOACHRM2SIGMAR1SCN8AGAA
SCHEMBL2455480 0.76 EPHX1 (0.39) SMN1; SMN2SIGMAR1GAAATMALDH1A1
SCHEMBL28932838 0.75 ADH1B (0.37) MAOASMN1; SMN2CHRM2SIGMAR1SCN8A
SCHEMBL7613236 0.75 CASR (0.43) CASRSIGMAR1GAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758929-B1 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORP (US) 2002-01-09 — — EP disclosed
EP-1152285-A2 Electrochromic mirrors and devices DONNELLY CORPORATION (US) 2001-11-07 — — EP disclosed
EP-0758929-A4 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORP (US) 1997-08-06 — — EP disclosed
EP-0758929-A1 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORPORATION (US) 1997-02-26 — — EP disclosed
WO-1995030495-A1 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORPORATION (US) 1995-11-16 — — WO disclosed
EP-0240919-A2 Method for coating fibers International Business Machines Corporation (US) 1987-10-14 — — EP disclosed
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