Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493873 | 0.84 | HSD17B10 (0.43) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL9329612 | 0.83 | ALDH1A1 (0.36) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL28602211 | 0.76 | CYP3A4 (0.46) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL5030574 | 0.73 | HSD17B10 (0.48) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL4447138 | 0.72 | KMT2A (0.41) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL30696544 | 0.72 | ESR2 (0.39) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL18690039 | 0.72 | ESR2 (0.39) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL1899394 | 0.71 | HSD17B10 (0.46) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL1009932 | 0.71 | HSD17B10 (0.46) | HSD17B10ALDH1A1KMT2ABRD4TDO2 | |
| SCHEMBL675595 | 0.71 | ALDH1A1 (0.50) | HSD17B10ALDH1A1KMT2ABRD4TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045115-A1 | Charge generation layer for electrophotographic imaging member and a process for making thereof | XEROX CORPORATION | 2002-04-18 | — | — | US | disclosed |
| EP-0149914-B1 | OVERCOATED ELECTROPHOTOGRAPHIC IMAGING MEMBER | XEROX CORPORATION (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0149914-A1 | Overcoated electrophotographic imaging member | XEROX CORPORATION (US) | 1985-07-31 | — | — | EP | disclosed |