Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616612 | 0.83 | HSD17B10 (0.34) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL141445 | 0.81 | HSD17B10 (0.50) | ALDH1A1HSD17B10TDO2AKT2CYP3A4 | |
| SCHEMBL1009932 | 0.77 | HSD17B10 (0.46) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL2327490 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KMT2ABRD4MAPT | |
| SCHEMBL5030574 | 0.76 | HSD17B10 (0.48) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL10493873 | 0.75 | HSD17B10 (0.43) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL28845278 | 0.75 | HSD17B10 (0.48) | ALDH1A1HSD17B10TDO2AKT2CYP3A4 | |
| SCHEMBL28602211 | 0.74 | CYP3A4 (0.46) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL1899394 | 0.73 | HSD17B10 (0.46) | ALDH1A1HSD17B10KMT2ABRD4TDO2 | |
| SCHEMBL675595 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KMT2ABRD4TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5343050-A | Organic electroluminescent device with low barrier height | KABUSHIKI KAISHA TOSHIBA (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0553950-A2 | Organic electroluminescent device | KABUSHIKI KAISHA TOSHIBA (JP) | 1993-08-04 | — | — | EP | disclosed |