Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515434 | 0.72 | ALDH1A1 (0.36) | TSHRALDH1A1TP53SLC7A5 | |
| SCHEMBL5161200 | 0.71 | CYP2D6 (0.41) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| SCHEMBL284728 | 0.71 | TSHR (0.40) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| SCHEMBL14387795 | 0.71 | TSHR (0.40) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| SCHEMBL3942875 | 0.71 | TSHR (0.40) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| SCHEMBL2374040 | 0.69 | TP53 (0.44) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| SCHEMBL9527915 | 0.69 | TSHR (0.38) | TSHRALDH1A1TP53SLC7A5CYP2D6 | |
| 2,2,3-Trimethylbutane SCHEMBL2103951 | 0.67 | ALDH1A1 (0.41) | TSHRALDH1A1TP53SLC7A5CYP2C19 | |
| Ethylene SCHEMBL28195307 | 0.67 | ALDH1A1 (0.36) | TSHRALDH1A1TP53SLC7A5 | |
| SCHEMBL27665731 | 0.67 | ALDH1A1 (0.36) | TSHRALDH1A1TP53SLC7A5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | claimed |
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | disclosed |
| EP-1027086-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | Artimplant AB (SE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999022780-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 1999-05-14 | — | — | WO | disclosed |