Guanidine

Guanidine

SCHEMBL7618155

N=C(N)N.P

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL28164760 0.94
Guanidine SCHEMBL28088958 0.94
Guanidine SCHEMBL5613752 0.93
Guanidine SCHEMBL29983942 0.93
Guanidine SCHEMBL11330173 0.93
Guanidine SCHEMBL2003 0.93
Guanidine SCHEMBL165720 0.93 NOS2 (0.42)
Guanidine SCHEMBL29102700 0.88
Guanidine SCHEMBL25310528 0.86
Guanidine SCHEMBL3310493 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110354902-B Process for preparing phosphine guanidine compound 苏州大学 2022-06-03 CN claimed
CN-110354902-A The method for preparing phosphine guanidine compound 苏州大学 2019-10-22 CN claimed
CN-108057460-A Application of disilylamine rare earth complex in catalyzing phosphine hydrogenation reaction of carbodiimide and diphenylphosphine 苏州大学 2018-05-22 CN claimed
CN-101121733-B Organometallic compounds ROHM & HAAS ELECT MAT 2012-05-23 CN claimed
CN-101440477-B Precursor compositions and methods ROHM & HAAS ELECT MAT 2012-01-11 CN claimed
CN-101440477-A Precursor compositions and methods ROHM & HAAS ELECT MAT (US) 2009-05-27 CN claimed
CN-101182339-A Metal-imino complexes suitable for use as vapor deposition precursors ROHM & HAAS ELECT MAT (US) 2008-05-21 CN claimed
CN-101121733-A Organometallic compounds ROHM & HAAS ELECT MAT (US) 2008-02-13 CN claimed
EP-0968219-B1 Guanidinium phosphanes, their production and their use CELANESE CHEM EUROPE GMBH (DE) 2002-07-17 EP claimed
CN-1243516-A Guanidinium phosphanes, their production and their use CELANESE GMBH (DE) 2000-02-02 CN claimed
CN-110354902-B Process for preparing phosphine guanidine compound 苏州大学 2022-06-03 CN disclosed
CN-110354902-B Process for preparing phosphine guanidine compound 苏州大学 2022-06-03 CN disclosed
CN-110354902-B Process for preparing phosphine guanidine compound 苏州大学 2022-06-03 CN disclosed
CN-108057460-B Application of disilylamine rare earth complex in catalyzing phosphine hydrogenation reaction of carbodiimide and diphenylphosphine 苏州大学 2020-07-14 CN disclosed
CN-108057460-B Application of disilylamine rare earth complex in catalyzing phosphine hydrogenation reaction of carbodiimide and diphenylphosphine 苏州大学 2020-07-14 CN disclosed
CN-101182339-A Metal-imino complexes suitable for use as vapor deposition precursors ROHM & HAAS ELECT MAT (US) 2008-05-21 CN disclosed
CN-101121734-A Organometallic compounds ROHM & HAAS ELECT MAT (US) 2008-02-13 CN disclosed
CN-101121733-A Organometallic compounds ROHM & HAAS ELECT MAT (US) 2008-02-13 CN disclosed
US-6187953-B1 A GUANIDINIUM PHOSPHINES USE AS CATALYST LIGANDS FOR THE CARBON-CARBON LINKAGE REACTIONS CELANESE GMBH (DE) 2001-02-13 US disclosed
CN-1243516-A Guanidinium phosphanes, their production and their use CELANESE GMBH (DE) 2000-02-02 CN disclosed