SCHEMBL7618458

SCHEMBL7618458

CCCC(Cl)CCCC(Cl)Cc1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
HTR1A P08908 1/20 0.39
HSPA5 P11021 1/20 0.38
AKR1B1 P15121 1/20 0.38
CYP2D6 P10635 3/20 0.35
HIF1A Q16665 1/20 0.35
CA12 O43570 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 4/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
CYP3A4 P08684 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29282747 0.81 HSPA5 (0.42) TSHRHSPA5AKR1B1CYP2D6HIF1A
SCHEMBL28303099 0.79 HSPA5 (0.46) TSHRHTR1AHSPA5AKR1B1CYP2D6
SCHEMBL7618016 0.75 TSHR (0.41) TSHRHTR1AHSPA5AKR1B1CYP2D6
SCHEMBL10423665 0.74 TYR (0.38) TSHRHIF1AHSD17B10CYP3A4LMNA
SCHEMBL6681406 0.74 SLC6A2 (0.46) KDM4ETAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL13010804 0.74 HSPA5 (0.45) TSHRHTR1AHSPA5AKR1B1CYP2D6
SCHEMBL15178323 0.74 HSPA5 (0.45) TSHRHTR1AHSPA5AKR1B1CYP2D6
Phenol SCHEMBL27516147 0.74 HTR1A (0.43) TSHRHTR1AAKR1B1TAAR1CYP3A4
SCHEMBL11025110 0.73 MPO (0.45) TSHRHTR1AHSPA5AKR1B1CYP2D6
SCHEMBL7618467 0.73 ESR1 (0.53) HIF1AKDM4EHSD17B10TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815155-B1 METATHESIS POLYMERIZATION CATALYST SOLUTION AND SYSTEM FOR PREPARING CROSS-LINKED POLYMERS TEIJIN METTON KABUSHIKI KAISHA (JP) 2002-08-07 EP disclosed
EP-0815155-A1 METATHESIS POLYMERIZATION CATALYST SOLUTION AND SYSTEM FOR PREPARING CROSS-LINKED POLYMERS Teijin-Metton Kabushiki Kaisha (JP) 1998-01-07 EP disclosed
WO-1997026291-A1 METATHESIS POLYMERIZATION CATALYST SOLUTION AND SYSTEM FOR PREPARING CROSS-LINKED POLYMERS TEIJIN-METTON KABUSHIKI KAISHA (JP) 1997-07-24 WO disclosed