SCHEMBL7619288

SCHEMBL7619288

Cc1ccc(C=CCc2ccc(N(c3ccccc3)c3ccc4c5c(cccc35)-c3ccccc3-4)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 2/20 0.33
APP P05067 1/20 0.32
MEN1 O00255 2/20 0.31
USP2 O75604 2/20 0.31
KMT2A Q03164 2/20 0.31
KCNA3 P22001 2/20 0.31
MAPT P10636 2/20 0.30
KDM4E B2RXH2 2/20 0.30
PABPC1 P11940 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPK1 P28482 1/20 0.30
CTNNB1 P35222 1/20 0.30
ATM Q13315 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP2C19 P33261 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18037044 0.86 KDM4E (0.37) TRPM8APPMEN1USP2KMT2A
SCHEMBL7619293 0.86 KDM4E (0.37) TRPM8APPMEN1USP2KMT2A
SCHEMBL29597568 0.86 KDM4E (0.37) TRPM8APPMEN1USP2KMT2A
SCHEMBL13358340 0.84 APP (0.39) TRPM8APPMEN1USP2KMT2A
SCHEMBL10128557 0.83 KDM4E (0.41) APPMEN1USP2KMT2AMAPT
SCHEMBL10072075 0.81 KDM4E (0.42) MEN1USP2KMT2AMAPTKDM4E
SCHEMBL6775821 0.77 TRPM8 (0.41) TRPM8APPMEN1USP2KMT2A
SCHEMBL13358232 0.77 PDK2 (0.34) TRPM8APPMEN1USP2KMT2A
SCHEMBL14010644 0.77 KDM4E (0.40) MEN1USP2KMT2AMAPTKDM4E
SCHEMBL13358328 0.77 APP (0.37) APPMEN1USP2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898882-B Coating comprising polymer layer, optical film and display device 罗门哈斯电子材料有限责任公司 2022-10-28 CN disclosed
CN-115023429-A Electroactive compounds 杜邦电子公司 2022-09-06 CN disclosed
CN-114940681-A Electroactive compounds 株式会社LG化学 2022-08-26 CN disclosed
CN-110023319-B Electroactive compounds 株式会社LG化学 2022-06-17 CN disclosed
CN-114514225-A Electroactive compounds 杜邦电子公司 2022-05-17 CN disclosed
CN-114080392-A Electroactive compounds 杜邦电子公司 2022-02-22 CN disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
CN-113501778-A Blue light-emitting compound 株式会社LG化学 2021-10-15 CN disclosed
CN-112898882-A Refractive index adjustable polymer 罗门哈斯电子材料有限责任公司 2021-06-04 CN disclosed
CN-107074763-B Blue light-emitting compound 株式会社LG化学 2021-01-05 CN disclosed
US-20020022151-A1 Organic electroluminescent device NEC CORPORATION (JP) 2002-02-21 US disclosed