Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047677 | 1.00 | KDM1A (0.47) | KDM1AMAOBHDAC9PNMTTSHR | |
| SCHEMBL11696762 | 0.90 | KDM1A (0.54) | KDM1ATSHRTP53CYP1A2CYP3A4 | |
| SCHEMBL6267106 | 0.79 | KDM1A (0.53) | KDM1AMAOBHDAC9TSHRALDH1A1 | |
| SCHEMBL29784907 | 0.79 | KDM1A (0.53) | KDM1AMAOBHDAC9TSHRALDH1A1 | |
| SCHEMBL11883933 | 0.78 | KDM1A (0.46) | KDM1AMAOBTSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL29189207 | 0.77 | KDM1A (0.52) | KDM1AMAOBHDAC9TSHRALDH1A1 | |
| SCHEMBL11166802 | 0.77 | HTR2A (0.47) | KDM1AMAOBHDAC9PNMT | |
| SCHEMBL30112838 | 0.75 | KDM1A (0.59) | KDM1AMAOBTSHRTP53CYP1A2 | |
| SCHEMBL1101137 | 0.75 | KDM1A (0.59) | KDM1AMAOBTSHRTP53CYP1A2 | |
| SCHEMBL6337745 | 0.75 | HDAC9 (0.49) | KDM1AMAOBHDAC9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002500211-A | — | — | 2002-01-08 | — | — | JP | claimed |
| EP-1044184-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | Pharm-Eco Laboratoires, Incorporated (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999035119-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | PHARM-ECO LABORATORIES, INC. (US) | 1999-07-15 | — | — | WO | claimed |