SCHEMBL5047677

SCHEMBL5047677

NC1(c2ccccc2)CCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.47
MAOB P27338 1/20 0.47
HDAC9 Q9UKV0 1/20 0.46
PNMT P11086 1/20 0.41
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7619310 1.00 KDM1A (0.47) KDM1AMAOBHDAC9PNMTTSHR
SCHEMBL11696762 0.90 KDM1A (0.54) KDM1ATSHRTP53CYP1A2CYP3A4
SCHEMBL6267106 0.79 KDM1A (0.53) KDM1AMAOBHDAC9TSHRALDH1A1
SCHEMBL29784907 0.79 KDM1A (0.53) KDM1AMAOBHDAC9TSHRALDH1A1
SCHEMBL11883933 0.78 KDM1A (0.46) KDM1AMAOBTSHRALDH1A1TDP1
Hydrochloric Acid SCHEMBL29189207 0.77 KDM1A (0.52) KDM1AMAOBHDAC9TSHRALDH1A1
SCHEMBL11166802 0.77 HTR2A (0.47) KDM1AMAOBHDAC9PNMT
SCHEMBL30112838 0.75 KDM1A (0.59) KDM1AMAOBTSHRTP53CYP1A2
SCHEMBL1101137 0.75 KDM1A (0.59) KDM1AMAOBTSHRTP53CYP1A2
SCHEMBL6337745 0.75 HDAC9 (0.49) KDM1AMAOBHDAC9TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO claimed
EP-0143075-B1 PROCESS FOR THE PREPARATION OF N-GLYCIDYL COMPOUNDS CIBA-GEIGY AG (CH) 1987-11-19 EP claimed
EP-0099338-B1 EPOXY RESIN SYSTEMS MODIFIED WITH THERMOPLASTIC RESINS CIBA-GEIGY AG (CH) 1986-05-14 EP claimed
US-4540769-A NITRATE, PERCHLORATE, ALPHA-HALO CARBOXYLATE OR SULFONATE CIBA-GEIGY CORPORATION (US) 1985-09-10 US claimed
EP-0143075-A1 Process for the preparation of N-glycidyl compounds CIBA-GEIGY AG (CH) 1985-05-29 EP claimed
EP-3762431-A1 ETHYLENE-PROPYLENE LINEAR COPOLYMERS AS VISCOSITY MODIFIERS ExxonMobil Chemical Patents Inc. (US) 2021-01-13 EP disclosed
WO-2019173598-A1 ETHYLENE-PROPYLENE LINEAR COPOLYMERS AS VISCOSITY MODIFIERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-12 WO disclosed
US-8076495-B2 Aromatic N-glycidylamines by catalysis of an aromatic aminehydrogen and epichlorohydrin using a lanthanum nitrate as a catalyst dissolved in propylene carbonate, then dehydrochlorinating HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2011-12-13 US disclosed
US-20080221342-A1 Process HUNTSMAN ADVANCED MATERIALS AMERICANS INC. (US) 2008-09-11 US disclosed
CN-100400525-C Process for the preparation of n-glycidylamines HUNTSMAN ADV MAT SWITZERLAND (CH) 2008-07-09 CN disclosed
EP-1656363-B1 PROCESS FOR THE PREPARATION OF N-GLYCIDYLAMINES HUNTSMAN ADV MAT SWITZERLAND (CH) 2007-10-10 EP disclosed
CN-1812976-A Process for the preparation of n-glycidylamines HUNTSMAN ADV MAT SWITZERLAND (CH) 2006-08-02 CN disclosed
EP-1656363-A2 PROCESS FOR THE PREPARATION OF N-GLYCIDYLAMINES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2006-05-17 EP disclosed
WO-2005003109-A2 PROCESS FOR THE PREPARATION OF N-GLYCIDYLAMINES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-01-13 WO disclosed
US-6011070-A TREATING AN INDIVIDUAL WHO ABUSES COCAINE, AN INDIVIDUAL WITH PARKINSON'S DISEASE OR AN INDIVIDUAL WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER ALLELIX-PHARM-ECO L.P. (US) 2000-01-04 US disclosed
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO disclosed
EP-0143075-B1 PROCESS FOR THE PREPARATION OF N-GLYCIDYL COMPOUNDS CIBA-GEIGY AG (CH) 1987-11-19 EP disclosed
US-4540769-A NITRATE, PERCHLORATE, ALPHA-HALO CARBOXYLATE OR SULFONATE CIBA-GEIGY CORPORATION (US) 1985-09-10 US disclosed
EP-0143075-A1 Process for the preparation of N-glycidyl compounds CIBA-GEIGY AG (CH) 1985-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221342-A1 Process PAH, TET2, PAM KDM1A 351/4885MAOB 122/4885HDAC9 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.