Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620024 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7614749 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7620869 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7614058 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7620987 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7615234 | 0.91 | MAPT (0.55) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL7619938 | 0.85 | MAPT (0.49) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL9056155 | 0.84 | S1PR2 (0.46) | FAAHCES1MAPTRXFP1LTB4R | |
| SCHEMBL9054936 | 0.82 | ACLY (0.35) | MAPTFFAR1LTB4RTDP1 | |
| SCHEMBL7619979 | 0.81 | FFAR1 (0.53) | FFAR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |