Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL15054617 | 0.98 | ALDH1A1 (0.44) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| Piperidine SCHEMBL7621076 | 0.88 | MEN1 (0.40) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| Phthalic Acid SCHEMBL5875074 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EALOX15TDP1ABCC1 | |
| Phthalic Acid SCHEMBL5875064 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EALOX15TDP1ABCC1 | |
| SCHEMBL78873 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| SCHEMBL29556927 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| Benzene SCHEMBL28103329 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| SCHEMBL20448823 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7536438 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 | |
| Phthalic Acid SCHEMBL29243281 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4EALOX15CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | claimed |
| US-5675009-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-10-07 | — | — | US | claimed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | claimed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | claimed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | claimed |
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | disclosed |
| US-5675009-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5663353-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5654433-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5652370-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-29 | — | — | US | disclosed |
| US-5650516-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-22 | — | — | US | disclosed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5631375-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5618940-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | disclosed |