Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL7619489 | 0.88 | ALDH1A1 (0.43) | MEN1LMNATHRBBLMKMT2A | |
| Pyrrolidine SCHEMBL15054617 | 0.86 | ALDH1A1 (0.44) | MEN1LMNATHRBBLMKMT2A | |
| Ortho-Phthalaldehyde SCHEMBL7621085 | 0.83 | LMNA (0.59) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL7606289 | 0.83 | LMNA (0.57) | MEN1LMNATHRBBLMKMT2A | |
| Salicyladehyde SCHEMBL6694640 | 0.79 | TRIM24 (0.67) | MEN1LMNATHRBBLMKMT2A | |
| Piperidine SCHEMBL27475822 | 0.75 | LMNA (0.43) | MEN1LMNATHRBBLMKMT2A | |
| Piperidine SCHEMBL1939590 | 0.75 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1HTTTP53 | |
| SCHEMBL31589131 | 0.74 | TRIM24 (0.59) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL14191557 | 0.74 | TRIM24 (0.59) | MEN1LMNATHRBBLMKMT2A | |
| Pyrrolidine SCHEMBL10325882 | 0.74 | MEN1 (0.41) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | claimed |
| US-5675009-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-10-07 | — | — | US | claimed |