Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617014 | 0.77 | ACHE (0.47) | ALDH1A1TSHRRAD52CHRM5CHRM1 | |
| SCHEMBL10446227 | 0.71 | MEN1 (0.48) | ALDH1A1RAD52SMN1; SMN2GAARAB9A | |
| Methylene Chloride SCHEMBL4914004 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL64593 | 0.67 | ALDH1A1 (0.68) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL24092255 | 0.67 | ALDH1A1 (0.38) | ALDH1A1TSHRRAD52CHRM5CHRM1 | |
| SCHEMBL6254474 | 0.67 | RAD52 (0.44) | ALDH1A1TSHRRAD52RAB9AL3MBTL1 | |
| SCHEMBL8989721 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TSHRRAD52CHRM5CHRM1 | |
| SCHEMBL11695543 | 0.66 | GSTP1 (0.41) | ALDH1A1TSHRRAD52CHRM5CHRM1 | |
| Benzene SCHEMBL11159553 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TSHRRAD52CHRM5CHRM1 | |
| SCHEMBL29446779 | 0.65 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433199-B1 | ANTITUMOR, ANTICANCER AGENTS | SHIONOGI BIORESEARCH CORPORATION | 2002-08-13 | — | — | US | disclosed |
| US-5969133-A | Bioreductive cytotoxic agents | SHIONGI BIORESEARCH CORP. (US) | 1999-10-19 | — | — | US | disclosed |