Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617430 | 0.79 | ELANE (0.40) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL6015972 | 0.76 | APP (0.40) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL31516345 | 0.71 | CNR1 (0.44) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL970742 | 0.71 | ALDH1A1 (0.54) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL4569764 | 0.70 | KMT2A (0.45) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL2491259 | 0.70 | ELANE (0.59) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL89569 | 0.69 | GSK3B (0.53) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL12670694 | 0.69 | ELANE (0.52) | NPC1RAB9AKDM4EELANEALDH1A1 | |
| SCHEMBL29277391 | 0.69 | ALDH1A1 (0.51) | KMT2ANPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL413483 | 0.69 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |