Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555699 | 0.90 | HPRT1 (0.51) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL6840618 | 0.86 | PDE3A (0.59) | HPRT1MEN1KMT2APDE3AHBB | |
| Hydrochloric Acid SCHEMBL5165704 | 0.85 | HBB (0.58) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL5166552 | 0.84 | MEN1 (0.54) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL7622544 | 0.84 | HPRT1 (0.51) | HPRT1MEN1KMT2APDE3AHBB | |
| Hydrochloric Acid SCHEMBL6380562 | 0.79 | HPRT1 (0.51) | HPRT1MEN1KMT2AHBBBLM | |
| Valine SCHEMBL8868227 | 0.78 | PDE3A (0.51) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL8447480 | 0.76 | MEN1 (0.69) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL5930380 | 0.76 | TK1 (0.55) | HPRT1MEN1KMT2APDE3AHBB | |
| SCHEMBL19662078 | 0.75 | HPRT1 (0.54) | HPRT1MEN1KMT2AHBBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885224-B1 | PROCESS FOR PREPARING GANCICLOVIR DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2002-12-18 | — | — | EP | disclosed |