Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13362009 | 1.00 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL25592953 | 1.00 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL13657213 | 1.00 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL16601877 | 1.00 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL18683146 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL16158586 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL9984795 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL24038360 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL13743009 | 0.83 | THRB (0.38) | THRBLMNA | |
| SCHEMBL13301751 | 0.82 | THRB (0.33) | THRBLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052489-A1 | PARTICLES, COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | THE JOHNS HOPKINS UNIVERSITY | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052489-A1 | PARTICLES, COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | MUC1, PDE6C, STRA6 | THRB 4280/4885LMNA 1592/4885GBA1 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.