Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14011507 | 0.83 | LMNA (0.58) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL28859554 | 0.83 | CTSK (0.53) | CTSKCTSSMAPT | |
| SCHEMBL13996047 | 0.83 | LMNA (0.58) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL13929428 | 0.83 | LMNA (0.58) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL7609304 | 0.82 | ATM (0.56) | CTSKCTSSRENMAPK1 | |
| SCHEMBL5862217 | 0.81 | CTSK (0.52) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL31633773 | 0.81 | CTSK (0.52) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL1573513 | 0.81 | CTSK (0.52) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL1783805 | 0.81 | CTSK (0.52) | MEN1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL14712709 | 0.81 | MAPT (0.43) | CTSKCTSSALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128185-A1 | Pharmaceutical compounds | HAWAII, UNIVERSITY OF | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128185-A1 | Pharmaceutical compounds | XPO5, XPOT, XPO1 | MEN1 45/4885KMT2A 3754/4885NPSR1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.