Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD5 | P21918 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 5/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376090 | 0.83 | KDM4E (0.56) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL1331372 | 0.81 | GRM1 (0.48) | DRD4HTR1AKDM4E | |
| SCHEMBL18948500 | 0.75 | CHRM1 (0.45) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL25563527 | 0.75 | MAPT (0.39) | KDM4EGAASGPL1GRIN2DGRIN3B | |
| SCHEMBL14853346 | 0.73 | PDE10A (0.43) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL16472352 | 0.72 | GRIN2D (0.49) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL15496957 | 0.72 | DRD2 (0.60) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL21424864 | 0.72 | GRIN2D (0.59) | DRD2DRD3DRD1DRD5DRD4 | |
| SCHEMBL17696420 | 0.70 | SMPD3 (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13725120 | 0.70 | SMPD3 (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432900-B1 | ANTISOILANTS | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-08-13 | — | — | US | disclosed |