SCHEMBL1331372

SCHEMBL1331372

CCN1CCN(c2ccccn2)CC(C)N(c2ccccn2)CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 7/20 0.48
DRD4 P21917 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
CYP2D6 P10635 1/20 0.47
GSK3B P49841 1/20 0.47
HTR1A P08908 1/20 0.44
POLB P06746 1/20 0.44
KCNH2 Q12809 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332188 0.86 KCNH2 (0.56) DRD4KDM4EHTR1APOLBKCNH2
SCHEMBL1331612 0.85 GRM1 (0.53) GRM1DRD4ALDH1A1KDM4EMAPT
SCHEMBL3867807 0.83 KDM4E (0.64) ALDH1A1KDM4EMAPTHTR1APOLB
SCHEMBL7620575 0.81 DRD2 (0.43) DRD4KDM4EHTR1A
SCHEMBL825296 0.80 PLD1 (0.44) GRM1ALDH1A1KDM4EMAPTCYP2D6
SCHEMBL31045967 0.80 GRM1 (0.49) GRM1DRD4CYP2D6GSK3BHTR1A
SCHEMBL3432554 0.78 PLD1 (0.65) GRM1DRD4ALDH1A1CYP2D6GSK3B
SCHEMBL28457545 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTHTR1APOLB
SCHEMBL15688241 0.77 KDM4E (0.57) DRD4ALDH1A1KDM4EMAPTHTR1A
SCHEMBL31046061 0.77 GRM1 (0.49) GRM1DRD4CYP2D6GSK3BKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US disclosed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US disclosed
US-9034785-B2 Accelerator solution and process for curing curable resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-05-19 US disclosed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP disclosed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US disclosed
US-8664306-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2014-03-04 US disclosed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US disclosed
US-8013044-B2 Liquid hardening CONOPCO, INC. (US) 2011-09-06 US disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed
EP-1208186-B1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2006-05-10 EP disclosed
US-6646122-B1 Triazacyclohenonane ligand UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-11-11 US disclosed