Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618387 | 0.88 | TSHR (0.46) | TSHRKIF11LMNAPTPRCKEAP1 | |
| SCHEMBL8408187 | 0.84 | TSHR (0.64) | TSHRLMNAPTPRCNPSR1ALDH1A1 | |
| SCHEMBL30764114 | 0.84 | TSHR (0.64) | TSHRLMNAPTPRCNPSR1ALDH1A1 | |
| SCHEMBL4323924 | 0.83 | TSHR (0.50) | TSHRLMNANPSR1ALDH1A1MAPT | |
| SCHEMBL30764106 | 0.82 | TSHR (0.57) | TSHRLMNANFE2L2NPSR1ALDH1A1 | |
| SCHEMBL29176796 | 0.82 | TSHR (0.57) | TSHRLMNANFE2L2NPSR1ALDH1A1 | |
| SCHEMBL16774768 | 0.82 | TSHR (0.57) | TSHRLMNANFE2L2NPSR1ALDH1A1 | |
| SCHEMBL19472450 | 0.82 | TSHR (0.45) | TSHRKIF11LMNAPTPRCKEAP1 | |
| SCHEMBL11991723 | 0.82 | KIF11 (0.43) | TSHRKIF11LMNAALDH1A1MAPT | |
| Dinitrophenylene SCHEMBL27713074 | 0.76 | TSHR (0.59) | TSHRKIF11LMNAALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020095057-A1 | Triarylphosphine oxide derivatives containing fluorine substituent and preparing method thereof | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-07-18 | — | — | US | claimed |
| US-20020095057-A1 | Triarylphosphine oxide derivatives containing fluorine substituent and preparing method thereof | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095057-A1 | Triarylphosphine oxide derivatives containing fluorine substituent and preparing method thereof | PFAS, PTK2, PARP1 | TSHR 1457/4885KIF11 760/4885LMNA 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.