Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.63 |
| ▸ | MC1R | Q01726 | 5/20 | 0.62 |
| ▸ | MC5R | P33032 | 4/20 | 0.62 |
| ▸ | MC3R | P41968 | 2/20 | 0.62 |
| ▸ | CTSC | P53634 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641919 | 0.87 | KMT2A (0.75) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL15145338 | 0.87 | KMT2A (0.75) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL15145353 | 0.86 | NLN (0.66) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL7615745 | 0.85 | HDAC8 (0.74) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL7617021 | 0.84 | HDAC8 (0.67) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL15398876 | 0.81 | CTSC (0.71) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL8706463 | 0.80 | KMT2A (0.65) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL6894596 | 0.80 | KMT2A (0.65) | HDAC8NLNCTSCMEN1KMT2A | |
| SCHEMBL5558741 | 0.80 | CA12 (0.52) | HDAC8NLNMC5RMC3RMC4R | |
| SCHEMBL7620303 | 0.79 | CTSC (0.72) | HDAC8NLNCTSCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | GHSR, GHRHR, SSTR3 | HDAC8 963/4885NLN 4447/4885MC1R 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.