Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713977 | 0.95 | CYP4F2 (0.45) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7622718 | 0.87 | LTB4R (0.44) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7616402 | 0.84 | MAPT (0.41) | SLC13A5 | |
| SCHEMBL7621132 | 0.82 | LTB4R (0.47) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7708014 | 0.81 | CYP4F2 (0.47) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7708036 | 0.81 | CYP4F2 (0.49) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7713972 | 0.77 | CYP4F2 (0.51) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7622711 | 0.74 | LTB4R (0.49) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 | |
| SCHEMBL8491129 | 0.73 | OPRM1 (0.39) | ALDH1A1 | |
| SCHEMBL7625472 | 0.72 | CYP2D6 (0.42) | LTB4RLTB4R2CYP4F2CYP4A11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |