Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621139 | 1.00 | FFAR1 (0.47) | FFAR1LTA4HCETPCNR2ACACB | |
| SCHEMBL7631661 | 0.89 | ALDH1A1 (0.51) | FFAR1LTA4HCETPCNR2ACACB | |
| SCHEMBL7631656 | 0.89 | ALDH1A1 (0.51) | FFAR1LTA4HCETPCNR2ACACB | |
| SCHEMBL7626154 | 0.88 | FFAR1 (0.42) | FFAR1LTA4HCETPCNR2ALDH1A1 | |
| SCHEMBL7624328 | 0.88 | FFAR1 (0.42) | FFAR1LTA4HCETPALDH1A1KDM4E | |
| SCHEMBL7624324 | 0.88 | FFAR1 (0.42) | FFAR1LTA4HCETPALDH1A1KDM4E | |
| SCHEMBL7622252 | 0.88 | FFAR1 (0.42) | FFAR1LTA4HCETPCNR2ALDH1A1 | |
| SCHEMBL7935886 | 0.87 | PPARG (0.42) | FFAR1CETPACACBACACAALDH1A1 | |
| SCHEMBL7935887 | 0.87 | PPARG (0.42) | FFAR1CETPACACBACACAALDH1A1 | |
| SCHEMBL7621811 | 0.87 | ALDH1A1 (0.47) | FFAR1CNR2ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916640-B1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-06-12 | — | — | EP | claimed |
| US-6288011-B1 | AGRICULTURE, EFFICIENCY | AMERICAN CYANAMID CO. | 2001-09-11 | — | — | US | claimed |
| EP-0916640-A1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | claimed |
| EP-0916640-B1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| US-6288011-B1 | AGRICULTURE, EFFICIENCY | AMERICAN CYANAMID CO. | 2001-09-11 | — | — | US | disclosed |
| EP-0916640-A1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |