Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935886 | 1.00 | PPARG (0.42) | PPARGPPARAFFAR1HTTSMN1; SMN2 | |
| SCHEMBL7631656 | 0.89 | ALDH1A1 (0.51) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7631661 | 0.89 | ALDH1A1 (0.51) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7624328 | 0.88 | FFAR1 (0.42) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7624324 | 0.88 | FFAR1 (0.42) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7626154 | 0.88 | FFAR1 (0.42) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7622252 | 0.88 | FFAR1 (0.42) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7621144 | 0.87 | FFAR1 (0.47) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7621139 | 0.87 | FFAR1 (0.47) | FFAR1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7622420 | 0.87 | ALDH1A1 (0.47) | PPARGPPARAFFAR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235754-B1 | USING 1,4-DIARYL-(2-FLUORO- OR 2,3-DIFLUORO-)-2-BUTENE | AMERICAN CYANAMID COMPANY | 2001-05-22 | — | — | US | disclosed |
| EP-0933027-A1 | Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites | American Cyanamid Company (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0916640-A1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |