SCHEMBL7621148

SCHEMBL7621148

CCC=C(F)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
CES1 P23141 4/20 0.39
CES2 O00748 3/20 0.39
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
LMNA P02545 1/20 0.35
PTGS2 P35354 1/20 0.35
HPGD P15428 2/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621134 1.00 ATM (0.40) ATMCES1CES2MTNR1AMTNR1B
SCHEMBL28825254 0.79 HDAC3 (0.36) ATMCES1CES2LMNAHPGD
SCHEMBL1226475 0.76 MTNR1A (0.52) ATMCES1CES2MTNR1AMTNR1B
SCHEMBL3680121 0.76 ATM (0.43) ATMCES1CES2MTNR1AMTNR1B
SCHEMBL94817 0.76 ATM (0.43) ATMCES1CES2MTNR1AMTNR1B
SCHEMBL16933937 0.75 CES1 (0.39) CES1CES2MAPK1TDP1MEN1
SCHEMBL11309464 0.75 CES1 (0.39) CES1CES2MAPK1TDP1MEN1
SCHEMBL11309461 0.75 CES1 (0.39) CES1CES2MAPK1TDP1MEN1
SCHEMBL1193963 0.74 KDM1A (0.42) ATMCES1CES2MTNR1AMTNR1B
SCHEMBL2490467 0.74 KDM1A (0.42) ATMCES1CES2MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929210-A A kind of synthetic method of the fluoro- 2,2- dichloro propionic aldehyde of pesticide intermediate 3,3,3- tri- 江苏扬农化工集团有限公司 2018-12-04 CN claimed
EP-0916640-B1 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents BASF AG (DE) 2002-06-12 EP disclosed