Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624865 | 0.96 | CRHR1 (0.46) | CRHR1TSHR | |
| SCHEMBL7534790 | 0.86 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL7590923 | 0.75 | CRHR1 (0.43) | CRHR1TSHR | |
| SCHEMBL7474332 | 0.72 | CRHR1 (0.42) | CRHR1TSHR | |
| SCHEMBL7625265 | 0.69 | CRHR1 (0.36) | CRHR1TSHR | |
| SCHEMBL7486581 | 0.65 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL20733330 | 0.64 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7539896 | 0.63 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL7625566 | 0.63 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL8194048 | 0.63 | CRHR1 (0.52) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448261-B1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS; TREATING ANXIETY, DEPRESSION, AND OTHER PSYCHIATRIC AND NEUROLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-10 | — | — | US | disclosed |
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |